PROBABILITY OF DISEASE EXTINCTION AND OUTBREAK IN A STOCHASTIC TUBERCULOSIS MODEL WITH FAST-SLOW PROGRESSION AND RELAPSE

Probability of disease extinction and outbreak in a stochastic tuberculosis model with fast-slow progression and relapse

A stochastic continuous-time Markov chain tuberculosis model with fast-slow progression and relapse is established to explore the impact of the demographic variation on TB transmission.At first, the extinction threshold and probability of the disease extinction and outbreak are obtained by applying the Eye Mask Pack multitype Galton-Waston branchin

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Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine

Abstract Background The essentially unlimited expansion potential and the pluripotency of human embryonic stem cells (hESCs) make them attractive for cell-based therapeutic purposes.Although hESCs can indefinitely proliferate in culture, unlike transformed cancer cells, they are endowed with a cell-intrinsic 3 Ply Dinner property termed mitochondri

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Lyme Disease Training and Knowledge Translation Resources Available to Canadian Healthcare Professionals: A Gray Literature Review

Introduction: Lyme Disease (LD) is the most common tick-borne c disease in North America.With the number of cases increasing yearly, Canadian healthcare professionals (HCP) rely on up-to-date and evidence-informed guidelines, instruction, and resources to effectively prevent, diagnose, and treat Lyme disease (LD).This review is the first of its kin

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